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112830-95-2

112830-95-2 Structure

112830-95-2 Structure
IdentificationBack Directory
[Name]

HU-210
[CAS]

112830-95-2
[Synonyms]

HU-210
HU-210 (solution)
HU-210/112830-95-2
HU-210 DEA Schedule I
HU-210 (Spice Cannabinoid)
HU-210 (exempt preparation)
HU 210 (100μg/mL in Methanol)
11-OH-Δ8-THC-1,1-dimethylheptyl
(-)-11-OH-Δ8-THC-1,1-dimethylheptyl
(6aR)-6aβ,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol
(6aR)-6aβ,7,10,10aα-Tetrahydro-6,6-dimethyl-1-hydroxy-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol
(6AR,10AR)-3(1,1-DIMETHYLHEPTYL)-6A,7,10,10A-TETRAHYDRO-1-HYDROXY-6,6-DIMETHYL-6H-DIBENZO[B,D]PYRAN-9-METHANOL
[6aR,(-)]-6a,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol
(6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol
(6AR)-TRANS-3-(1,1-DIMETHYLHEPTYL)-6A,7,10,10A-TETRAHYDRO-1-HYDROXY-6,6-DIMETHYL-6H-DIBENZO[B,D]PYRAN-9-METHANOL
(6AR,10AR)-3-(1,1'-DIMETHYLHEPTYL)-6A,7,10,10A-TETRAHYDRO-1-HYDROXY-6,6-DIMETHYL-6H-DIBENZO[B,D]PYRAN-9-METHANOL
6H-Dibenzo[b,d]pyran-9-Methanol,3-(1,1-diMethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-diMethyl-,(6aR,10aR)-
(6aR)-trans-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-(6H)-dibenzo[b.d]pyran-9-methanol
[EINECS(EC#)]

200-659-6
[Molecular Formula]

C25H38O3
[MDL Number]

MFCD01074786
[MOL File]

112830-95-2.mol
[Molecular Weight]

386.57
Chemical PropertiesBack Directory
[Boiling point ]

470.1±45.0 °C(Predicted)
[density ]

1.030±0.06 g/cm3(Predicted)
[Fp ]

9℃
[storage temp. ]

−20°C
[solubility ]

DMSO: soluble
[form ]

solid
[pka]

9.72±0.60(Predicted)
[BRN ]

4298162
[Stability:]

Hygroscopic
Safety DataBack Directory
[Hazard Codes ]

F,T
[Risk Statements ]

11-23/24/25-39/23/24/25
[Safety Statements ]

7-16-36/37-45
[RIDADR ]

UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ]

3
[HS Code ]

29329990
Hazard InformationBack Directory
[Description]

HU-210 (exempt preparation) (Item No. 90083) is an analytical reference standard categorized as a synthetic cannabinoid. HU-210 is regulated as a Schedule I compound in the United States. HU-210 (exempt preparation) (Item No. 90083) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
[Chemical Properties]

liquid
[Uses]

A synthetic agonist analog of ?9-Tetrahydro Cannabinol (T293200), which is the primary psychoactive component of marijuana. HU-210 is a potent central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist. It binds to neuroblastoma cell membrane CB1 receptors with about the same affinity as CP-55940. Controlled Substance.
[Definition]

ChEBI: HU-210 is a 1-benzopyran.
[Biological Activity]

A highly potent cannabinoid receptor agonist (K i values are 0.061 and 0.52 nM at cloned human CB 1 and CB 2 receptors respectively). Induces spatial memory deficits and suppresses hippocampal firing rates in rats. Also displays agonist activity at GPR55 (EC 50 = 26 nM). Also available as part of the Cannabinoid Receptor Agonist Tocriset™ .
[References]

[1] D M SLIPETZ. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase.[J]. Molecular Pharmacology, 1995, 48 2: 352-361.
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