| Identification | Back Directory | [Name]
HU-210 | [CAS]
112830-95-2 | [Synonyms]
HU-210 HU-210 (solution) HU-210/112830-95-2 HU-210 DEA Schedule I HU-210 (Spice Cannabinoid) HU-210 (exempt preparation) HU 210 (100μg/mL in Methanol) 11-OH-Δ8-THC-1,1-dimethylheptyl (-)-11-OH-Δ8-THC-1,1-dimethylheptyl (6aR)-6aβ,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol (6aR)-6aβ,7,10,10aα-Tetrahydro-6,6-dimethyl-1-hydroxy-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol (6AR,10AR)-3(1,1-DIMETHYLHEPTYL)-6A,7,10,10A-TETRAHYDRO-1-HYDROXY-6,6-DIMETHYL-6H-DIBENZO[B,D]PYRAN-9-METHANOL [6aR,(-)]-6a,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-(1,1-dimethylheptyl)-6H-dibenzo[b,d]pyran-9-methanol (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol (6AR)-TRANS-3-(1,1-DIMETHYLHEPTYL)-6A,7,10,10A-TETRAHYDRO-1-HYDROXY-6,6-DIMETHYL-6H-DIBENZO[B,D]PYRAN-9-METHANOL (6AR,10AR)-3-(1,1'-DIMETHYLHEPTYL)-6A,7,10,10A-TETRAHYDRO-1-HYDROXY-6,6-DIMETHYL-6H-DIBENZO[B,D]PYRAN-9-METHANOL 6H-Dibenzo[b,d]pyran-9-Methanol,3-(1,1-diMethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-diMethyl-,(6aR,10aR)- (6aR)-trans-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-(6H)-dibenzo[b.d]pyran-9-methanol | [EINECS(EC#)]
200-659-6 | [Molecular Formula]
C25H38O3 | [MDL Number]
MFCD01074786 | [MOL File]
112830-95-2.mol | [Molecular Weight]
386.57 |
| Chemical Properties | Back Directory | [Boiling point ]
470.1±45.0 °C(Predicted) | [density ]
1.030±0.06 g/cm3(Predicted) | [Fp ]
9℃ | [storage temp. ]
−20°C | [solubility ]
DMSO: soluble | [form ]
solid | [pka]
9.72±0.60(Predicted) | [BRN ]
4298162 | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
HU-210 (exempt preparation) (Item No. 90083) is an analytical reference standard categorized as a synthetic cannabinoid. HU-210 is regulated as a Schedule I compound in the United States. HU-210 (exempt preparation) (Item No. 90083) is provided as a DEA exempt preparation. This product is intended for research and forensic applications. | [Chemical Properties]
liquid | [Uses]
A synthetic agonist analog of ?9-Tetrahydro Cannabinol (T293200), which is the primary psychoactive component of marijuana. HU-210 is a potent central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist. It binds to neuroblastoma cell membrane CB1 receptors with about the same affinity as CP-55940.
Controlled Substance. | [Definition]
ChEBI: HU-210 is a 1-benzopyran. | [Biological Activity]
A highly potent cannabinoid receptor agonist (K i values are 0.061 and 0.52 nM at cloned human CB 1 and CB 2 receptors respectively). Induces spatial memory deficits and suppresses hippocampal firing rates in rats. Also displays agonist activity at GPR55 (EC 50 = 26 nM). Also available as part of the Cannabinoid Receptor Agonist Tocriset™ . | [References]
[1] D M SLIPETZ. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase.[J]. Molecular Pharmacology, 1995, 48 2: 352-361.
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