| Identification | Back Directory | [Name]
R(-)-NIGULDIPINE HCL | [CAS]
113145-70-3 | [Synonyms]
R(-)-NIGULDIPINE HCL
R(-)-NIGULDIPINE HYDROCHLORIDE (B859-35)
(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-(4,4-diphenyl-1-piperidinyl)propylmethy
(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid,3-(4,4-diphenyl-1-piperidinyl)propylmethylesterhydrochloride | [Molecular Formula]
C36H40ClN3O6 | [MDL Number]
MFCD00905004 | [MOL File]
113145-70-3.mol | [Molecular Weight]
646.18 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
methanol: soluble | [color ]
pale yellow | [Optical Rotation]
[α]23/D 12.5°, c = 0.14 in methanol(lit.) | [InChIKey]
MHOSUIMBPQVOEU-MGDILKBHSA-N | [SMILES]
Cl.COC(=O)C1=C(C)NC(C)=C([C@@H]1c2cccc(c2)[N+]([O-])=O)C(=O)OCCCN3CCC(CC3)(c4ccccc4)c5ccccc5 |
| Hazard Information | Back Directory | [Uses]
(R)-(-)-Niguldipine Hydrochloride is a potent chemosensitizer in multidrug resistant cells. | [Biological Activity]
L-type Ca 2+ channel blocker and α 1A -adrenoceptor antagonist; less active enantiomer. | [Biochem/physiol Actions]
Less active enantiomer |
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