| Identification | Back Directory | [Name]
GLICENTIN-RELATED POLYPEPTIDE (HUMAN) | [CAS]
1132745-52-8 | [Synonyms]
GRPP (HUMAN)
Human GRPP peptid
PROGLUCAGON (1-30) (HUMAN)
PREPROGLUCAGON (21-50) (HUMAN)
GLICENTIN-RELATED POLYPEPTIDE (HUMAN)
Preproglucagon (21-50) (huMan), Proglucagon (1-30) (huMan), Glicentin-Related Polypeptide (huMan)
ARG-SER-LEU-GLN-ASP-THR-GLU-GLU-LYS-SER-ARG-SER-PHE-SER-ALA-SER-GLN-ALA-ASP-PRO-LEU-SER-ASP-PRO-ASP-GLN-MET-ASN-GLU-ASP
H-ARG-SER-LEU-GLN-ASP-THR-GLU-GLU-LYS-SER-ARG-SER-PHE-SER-ALA-SER-GLN-ALA-ASP-PRO-LEU-SER-ASP-PRO-ASP-GLN-MET-ASN-GLU-ASP-OH
L-Aspartic acid, L-arginyl-L-seryl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-seryl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-alanyl-L-seryl-L-glutaminyl-L-alanyl-L-α-aspartyl-L-prolyl-L-leucyl-L-seryl-L-α-aspartyl-L-prolyl-L-α-aspartyl-L-glutaminyl-L-methiony... | [Molecular Formula]
C136H215N41O58S | [MDL Number]
MFCD08458592 | [MOL File]
1132745-52-8.mol | [Molecular Weight]
3384.47 |
| Chemical Properties | Back Directory | [density ]
1.62±0.1 g/cm3(Predicted) | [Sequence]
Arg-Ser-Leu-Gln-Asp-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Ser-Ala-Ser-Gln-Ala-Asp-Pro-Leu-Ser-Asp-Pro-Asp-Gln-Met-Asn-Glu-Asp |
| Hazard Information | Back Directory | [Uses]
GRPP (human) is a 30 amino acid Gcg-derived peptide. GRPP (human) causes slight increases in plasma insulin and decreases in plasma glucagon. GRPP (human) does not affect insulin secretion in rat islets[1]. | [References]
[1] Lynda Whiting, et al. Glicentin-related pancreatic polypeptide inhibits glucose-stimulated insulin secretion from the isolated pancreas of adult male rats. Physiol Rep. 2015 Dec;3(12):e12638. DOI:10.14814/phy2.12638 |
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