| Identification | Back Directory | [Name]
6-JOE SE | [CAS]
113394-23-3 | [Synonyms]
6-JOE, SE
6-CARBOXY-4',5'-DICHLORO-2',7"-*DIMETHOXYFLUOROSCEI
6-Carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein
6-CARBOXY-4',5'-DICHLORO-2',7'-DIMETHOXYFLUORESCEIN, SUCCINIMIDYL ESTER
6-CARBOXY-4',5'-DICHLORO-2',7'-DIMETHOXYFLUORESCEIN N-HYDROXYSUCCINIMIDE ESTER
6-Joe, SE [6-Carboxy-4',5'-Dichloro-2',7'-DiMethoxyfluorescein, SucciniMidyl Ester]
6-JOE, SE [6-Carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein, succinimidyl ester] *CAS#: 113394-23-3*
2,5-Dioxopyrrolidin-1-yl 4',5'-dichloro-3',6'-dihydroxy-2',7'-diMethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylate
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C27H17Cl2NO11 | [MDL Number]
MFCD01311845 | [MOL File]
113394-23-3.mol | [Molecular Weight]
602.33 |
| Chemical Properties | Back Directory | [Boiling point ]
835.6±75.0 °C(Predicted) | [density ]
1.79±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
water: slightly soluble | [form ]
solid | [pka]
7.73±0.20(Predicted) | [color ]
red | [Water Solubility ]
water: slightly soluble | [λmax]
(78,000 at 521 nm in 50 mmol phosphate bufferpH 12) | [Major Application]
diagnostic assay manufacturing
hematology
histology | [InChIKey]
UUVBVONAGUSCCH-UHFFFAOYSA-N | [SMILES]
COc1cc2c(Oc3c(Cl)c(O)c(OC)cc3C24OC(=O)c5ccc(cc45)C(=O)ON6C(=O)CCC6=O)c(Cl)c1O |
| Hazard Information | Back Directory | [Uses]
6-JOE SE is an automated DNA sequencing fluorophore. Dyes and metabolites. | [Uses]
Amine-Reactive Fluorescent probe, 6-JOE, SE has similar absorption and emission spectra of rhodamine 6G, and is mainly used in automated DNA sequencing. | [General Description]
A traditional fluorophore used in automated DNA sequencing. Characterized by an intermediate-wavelength spectra, high quantum yield, and low pH sensitivity in the physiological range. |
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