| Identification | Back Directory | [Name]
KN92 phosphate | [CAS]
1135280-28-2 | [Synonyms]
CS-1093
KN92-H3PO4
KN 92; KN92
KN92 phosphate
KN 92 phosphate
KN-92 (phosphate) | [Molecular Formula]
C24H28ClN2O7PS | [MDL Number]
MFCD24369012 | [MOL File]
1135280-28-2.mol | [Molecular Weight]
554.98 |
| Chemical Properties | Back Directory | [storage temp. ]
= -70C | [solubility ]
≥25 mg/mL in DMSO; insoluble in H2O; ≥43.1 mg/mL in EtOH with gentle warming | [form ]
Viscous liquid | [color ]
White to off-white | [InChIKey]
XRQHWVVDNMJDEQ-IPZCTEOASA-N | [SMILES]
[P](=O)(O)(O)O.[S](=O)(=O)(Nc2c(cccc2)CN(C\C=C\c3ccc(cc3)Cl)C)c1ccc(cc1)OC |
| Hazard Information | Back Directory | [Uses]
KN-92 is a useful negative control for KN-93. | [General Description]
Useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM kinase II inhibitor. | [Biological Activity]
kn-92 is the inactive analog of ca2+/calmodulin-dependent kinase ii (camkii) inhibitor kn-93. kn-92 has been often used as negative control for kn-93.kn-92 significantly reduced the sustained current amplitudes at the end of the 5-s depolarizing pulses of a wide range of kv channels such as kv1.5 and kv1.2 [1]. | [Biochem/physiol Actions]
Cell permeable: yes | [storage]
Store at -20°C | [References]
[1]. rezazadeh s, claydon tw, fedida d.kn-93(2-[n-(2-hydroxyethyl)]-n-(4-methoxybenzenesulfonyl)]amino-n-(4-chlorocinnamyl)-n-methylbenzylamine), a calcium/calmodulin-dependent protein kinase ii inhibitor, is a direct extracellular blocker of voltage-gated potassium channels.j pharmacolexpther. 2006 apr;317(1):292-9. |
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
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| Website: |
www.spiropharma.com.cn |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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