| Identification | Back Directory | [Name]
2'-O-methyl-2-thiouridine | [CAS]
113886-72-9 | [Synonyms]
2'-O-methyl-2-thiouridine
2-thio-2'-O-methyluridine
Uridine, 2'-O-methyl-2-thio-
2’-O-Methyl-2-thiouridine, RNA-modified nucleoside s2Um | [Molecular Formula]
C10H14N2O5S | [MOL File]
113886-72-9.mol | [Molecular Weight]
274.29 |
| Hazard Information | Back Directory | [Uses]
2’-O-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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