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1142057-18-8

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1142057-18-8 Structure

1142057-18-8 Structure
IdentificationBack Directory
[Name]

IRC 083864
[CAS]

1142057-18-8
[Synonyms]

IRC083864
IRC-083864
IRC 083864
[Molecular Formula]

C28H25F2N5O5S
[MOL File]

1142057-18-8.mol
[Molecular Weight]

581.59
Hazard InformationBack Directory
[Uses]

IRC-083864 is an inhibitor of CDC25 phosphatase. IRC-083864 inhibits the activity of recombinant human full-length CDC25 phosphatase with an IC50 value of 23 nM. IRC-083864 inhibits cell viability with an IC50 value of 47 nM on the HL60 cell line[1].
[References]

[1] Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124(6):1449-56. DOI:10.1002/ijc.24080
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