| Identification | Back Directory | [Name]
C6 NBD SAFINGOL | [CAS]
114301-97-2 | [Synonyms]
NBD-C6-SAFINGOL
C6 NBD SAFINGOL
C6 NBD SPHINGANINE
N-ACYL-SPHINGANINE (C6 NBD)
N-(NBD-AMINOCAPROYL)SAFINGOL
N-(NBD-AMINOCAPROYL)SPHINGANINE
C6 NBD dihydro Ceramide (d18:0/6:0)
N-(6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]CAPROYL)-SPHINGANINE
N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]HEXANOYL]-SPHINGANINE
N-(6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]CAPROYL)-L-THREO-SPHINGANINE
N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]HEXANOYL]-SPHINGANINE;C6-NBD SPHINGANINE
C6-NBD Sphinganine, N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]caproyl]-sphinganine
NBD-C6-Safingol, N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]caproyl]-L-threo-sphinganine
N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanamide
Hexanamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]- | [EINECS(EC#)]
309-560-3 | [Molecular Formula]
C30H51N5O6 | [MDL Number]
MFCD02259240 | [MOL File]
114301-97-2.mol | [Molecular Weight]
577.76 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 0.5 mg/ml | [form ]
A crystalline solid | [color ]
Yellow to orange | [InChI]
InChI=1S/C30H51N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h20-21,25,27,31,36-37H,2-19,22-23H2,1H3,(H,32,38)/t25-,27+/m0/s1 | [InChIKey]
GEZLBJRDZRUTOE-AHKZPQOWSA-N | [SMILES]
C(N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC)(=O)CCCCCNC1C2C(C([N+]([O-])=O)=CC=1)=NON=2 |
| Hazard Information | Back Directory | [Description]
C6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C6 ceramide in the inhibition of viral glycoprotein transport through the Golgi. C6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane. C6 NBD dihydro ceramide (d18:0/6:0) is structurally identical to C6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone. | [Uses]
C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid[1]. | [References]
[1] Landoni M, et al. UV-MALDI mass spectrometry analysis of NBD-glycosphingolipids without an external matrix. J Am Soc Mass Spectrom. 2008 Jul;19(7):923-6. DOI:10.1016/j.jasms.2008.04.017 |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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