| Identification | Back Directory | [Name]
CAY10599 | [CAS]
1143573-33-4 | [Synonyms]
CAY10599
CAY10599 Exclusive
JWJGBYOYIUOQEB-UHFFFAOYSA-N
Propanoic acid, 2-[[1-[3-[4-([1,1'-biphenyl]-4-ylcarbonyl)-2-propylphenoxy]propyl]-1,2,3,4-tetrahydro-5-quinolinyl]oxy]-2-methyl- | [Molecular Formula]
C38H41NO5 | [MDL Number]
MFCD18382106 | [MOL File]
1143573-33-4.mol | [Molecular Weight]
591.74 |
| Hazard Information | Back Directory | [Description]
CAY10599 is an agonist of peroxisome proliferator-activated receptor γ (PPARγ; EC50 = 0.05 μM in a transactivation assay). It is selective for PPARγ over PPARα and PPARδ (EC50s = 3.99 and >10 μM, respectively, in transactivation assays). | [Uses]
PPARγ agonist 11 (compound 20) is a selective agonist of PPARγ (EC50: 0.1 μM)[1]. | [Definition]
ChEBI: 2-[[1-[3-[4-([1,1'-biphenyl]-4-ylcarbonyl)-2-propylphenoxy]propyl]-1,2,3,4-tetrahydro-5-quinolinyl]oxy]-2-methyl-propanoic acid is a member of benzophenones. | [References]
[1] Lin CH, et al. Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists. J Med Chem. 2009 Apr 23;52(8):2618-22. DOI:10.1021/jm801594x |
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