ChemicalBook--->CAS DataBase List--->114547-31-8

114547-31-8

114547-31-8 Structure

114547-31-8 Structure
IdentificationBack Directory
[Name]

GALANIN, RAT
[CAS]

114547-31-8
[Synonyms]

GALANIN, RAT
Galanine【rat】
GALANIN RATGALANIN
Rat galanin-(1-29)
Galanine(1-29)【rat】
Galanin (mouse, rat)
Galanin(1-29)(rat,mouse)
Galanin, rat, ≥97% (HPLC)
GWTLNSAGYLLGPHAIDNHRSFSDKHGLT-NH2
GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-HIS-ALA-ILE-ASP-ASN-HIS-ARG-SER-PHE-SER-ASP-LYS-HIS-GLY-LEU-THR-NH2
H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-HIS-ALA-ILE-ASP-ASN-HIS-ARG-SER-PHE-SER-ASP-LYS-HIS-GLY-LEU-THR-NH2
L-Threoninamide,glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-histidyl-L-alanyl-L-isoleucyl-L-a-aspartyl-L-asparaginyl-L-histidyl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-a-aspa
Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-histidyl-L-alanyl-L-isoleucyl-L-a-aspartyl-L-asparaginyl-L-histidyl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-a-aspartyl-L-lysyl-L-h
L-Threoninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-histidyl-L-alanyl-L-isoleucyl-L-α-aspartyl-L-asparaginyl-L-histidyl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-α-aspartyl-L-lysyl-L-histidylglycyl-L-leucyl-
[Molecular Formula]

C141H211N43O41
[MDL Number]

MFCD00133354
[MOL File]

114547-31-8.mol
[Molecular Weight]

3164.45
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

powder
[color ]

White
[Water Solubility ]

Soluble to 1 mg/ml in water
[Sequence]

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Galanin (1-29)(rat, mouse) is a non-selective galanin receptor agonist, with Kis of 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively. Anticonvulsant effect[1][2].
[storage]

-20°C
[References]

[1] Wang S, et al. Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes. J Biol Chem. 1997;272(51):31949-31952. DOI:10.1074/jbc.272.51.31949
[2] Mazarati A, et al. Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: The effects of subtype-selective agonists and the role of G-protein-mediated signaling. J Pharmacol Exp Ther. 2006;318(2):700-708. DOI:10.1124/jpet.106.104703
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