| Identification | Back Directory | [Name]
METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE
| [CAS]
114676-69-6 | [Synonyms]
Boc-Cis-D-Hyp-OMe
cis-Boc-d-Hyp-Ome
N-Boc-cis-D-Hyp-Ome
(2R,4R)-1-Boc-4-hydroxypyrroL
CIS-1-BOC-4-HYDROXY-D-PROLINATE
(Tert-Butoxy)Carbonyl D-cis-Hyp-OMe
Methyl cis-Boc-4-hydroxy-D-prolinate
Methy cis-1-Boc-4-hydroxy-D-prolinate
Methyl cis-1-Boc-4-hydroxy-D-prolinate
Boc-cis-4-Hydroxy-D-proline methyl ester
N-Boc-cis-4-hydroxy-D-proline methyl ester
(2R,4R)-N-Boc-4-hydroxyproline methyl ester
N-Boc-cis-4-hydroxy-D-prolinemethylester,95%
METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE USP/EP/BP
(2R,4R)-N-Boc-cis-4-hydroxy-D-proline methyl ester
Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate
N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester
(2R,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy
(2R,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate
1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
O1-tert-Butyl O2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester
(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester
1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)- | [EINECS(EC#)]
675-952-9 | [Molecular Formula]
C11H19NO5 | [MDL Number]
MFCD00797548 | [MOL File]
114676-69-6.mol | [Molecular Weight]
245.27 |
| Chemical Properties | Back Directory | [Melting point ]
76 °C | [alpha ]
63° (C=1,EtOH) | [Boiling point ]
335.2±42.0 °C(Predicted) | [density ]
1.216±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [form ]
Powder | [pka]
14.27±0.40(Predicted) | [color ]
White | [InChI]
InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m1/s1 | [InChIKey]
MZMNEDXVUJLQAF-HTQZYQBOSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@@H]1C(OC)=O |
| Hazard Information | Back Directory | [Uses]
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (N-Boc-cis-4-hydroxy-D-proline methyl ester) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | [IC 50]
Non-cleavable Linker |
|
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 18918157536; |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|