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Aganirsen is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1). | [References]
[1] Cursiefen C, Viaud E, Bock F, et al. Aganirsen antisense oligonucleotide eye drops inhibit keratitis-induced corneal neovascularization and reduce need for transplantation: the I-CAN study.?Ophthalmology. 2014;121(9):1683-1692. DOI:10.1016/j.ophtha.2014.03.038 |
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