| Identification | Back Directory | [Name]
1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)imidazo[1,5-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)- | [CAS]
1152810-23-5 | [Synonyms]
Sheng Gelieting
1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)imidazo[1,5-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)- | [Molecular Formula]
C17H16F6N4O | [MOL File]
1152810-23-5.mol | [Molecular Weight]
406.33 |
| Chemical Properties | Back Directory | [Boiling point ]
525.3±50.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [form ]
Oil | [pka]
7.29±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Sheng Gelieting (CGT-8012) is a dipeptidy peptidase-IV enzyme (DP-IV) inhibitor. Sheng Gelieting has great DP-IV inhibition activity with an IC50 value of 87 nM. Sheng Gelieting can be used for curing or preventing diseases relevant to the dipeptidy peptidase-IV enzyme, such as the diabetes, particularly the II-type diabete[1]. | [References]
[1] Qiang Yu, et al. Beta-amino tetrahydropyrazine, tetrahydropyrimidine and tetrahydropyridine used as dipeptidy peptidase inhibitors for curing or preventing diabetes. Patent. CN101899047A. |
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