| Identification | Back Directory | [Name]
3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile | [CAS]
1153949-38-2 | [Synonyms]
β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile
3-cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]propanenitrile
1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile
racemic 3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile | [Molecular Formula]
C17H26BN3O2 | [MDL Number]
MFCD18206946 | [MOL File]
1153949-38-2.mol | [Molecular Weight]
315.22 |
| Chemical Properties | Back Directory | [Boiling point ]
471.8±25.0 °C(Predicted) | [density ]
1.13 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DCM, Methanol | [form ]
Solid | [pka]
1.71±0.10(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Uses]
β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile is an intermediate in the synthesis of Ruxolitinib (R701995), a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis. |
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