| Identification | Back Directory | [Name]
L-GLUTAMIC-3-13C ACID | [CAS]
115473-51-3 | [Synonyms]
L-GLUTAMIC-3-13C ACID
l-glutamic acid-3-13c
L-GLUTAMIC-3-13C ACID, 99 ATOM % 13C | [Molecular Formula]
C5H9NO4 | [MDL Number]
MFCD00190316 | [MOL File]
115473-51-3.mol | [Molecular Weight]
148.14 |
| Chemical Properties | Back Directory | [Melting point ]
205 °C (dec.) (lit.) | [form ]
solid | [Optical Rotation]
[α]25/D +31.0°, c = 2 in 5 M HCl | [InChI]
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1/i1+1 | [InChIKey]
WHUUTDBJXJRKMK-AANACRNLSA-N | [SMILES]
N[C@@H]([13CH2]CC(O)=O)C(O)=O | [CAS Number Unlabeled]
56-86-0 |
| Hazard Information | Back Directory | [Uses]
L-Glutamic acid-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. | [IC 50]
NMDA Receptor | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7. DOI:10.1016/0304-3940(77)90068-4 |
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