| Identification | Back Directory | [Name]
1-adamantylaspartate | [CAS]
115545-59-0 | [Synonyms]
1-adamantylaspartate
beta-1-Adamantylaspartic acid
1Adamantylaspartate,1 Adamantylaspartate
L-Aspartic acid, 4-tricyclo[3.3.1.13,7]dec-1-yl ester | [Molecular Formula]
C14H21NO4 | [MOL File]
115545-59-0.mol | [Molecular Weight]
267.32 |
| Hazard Information | Back Directory | [Uses]
1-Adamantylaspartate is a newly developed β-β-1-imidopropionic acid used to synthesize the C-terminal octapeptide of the β subunit of human chorionic gonadotropin (hCG) and the hexadecapeptide of the α subunit of the insulin receptor (30-55) by conventional solution methods and solid phase methods, aiming to inhibit the formation of asparagine during the synthesis of asparagyl peptides. Studies have shown that β-β-1-imidopropionic acid is an effective protector of the β-carboxyl function of aspartic acid residues. | [References]
[1] Amino Acids and Peptides. XXV.: Application of Newly Developed β-1-and β-2-Adamantylaspartates to Peptide Synthesis by Solid Phase and Conventional Solution |
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