| Identification | Back Directory | [Name]
TubeiMoside II | [CAS]
115810-12-3 | [Synonyms]
TubeiMoside B
Tubeimoside Ⅱ
TubeiMoside II
Tubeimoside II, BR
Tubeimoside BTubeimoside II
Tubeimoside II (Tubeimoside-B)
Olean-12-en-28-oicacid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-mrabinopyranosyl]-b-D-glucopyranosyl]oxy]-2,16,23-trihydroxy-,28-(O-b-D-xylopyrano
Olean-12-en-28-oicacid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-a-L-arabinopyranosyl]-b-D-glucopyranosyl]oxy]-2,16,23-trihydroxy-,28-(O-b-D-xylopyranosyl-(1?3)-O-6-deoxy-a-L-mannop
Olean-12-en-28-oicacid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-a-L-arabinopyranosyl]-b-D-glucopyranosyl]oxy]-2,16,23-trihydroxy-,28-(O-b-D-xylopyranosyl-(1?3)-O-6-deoxy-a-L-mannopyranosyl-(1?2)-a-L-arabinopyranosyl) ester, int
Olean-12-en-28-oic acid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-α-L-arabinopyranosyl]-β-D-glucopyranosyl]oxy]-2,16,23-trihydroxy-, 28-(O-β-D-xylopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl) ester, intramol. 4''(3)→4''(28)-ester, (2β,3β,4α,16α)- | [Molecular Formula]
C63H98O30 | [MDL Number]
MFCD28009144 | [MOL File]
115810-12-3.mol | [Molecular Weight]
1335.45 |
| Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
2-8°C | [solubility ]
Soluble in DMSO and methanol; | [form ]
Powder | [pka]
12.54±0.70(Predicted) | [color ]
White to off-white | [Water Solubility ]
insoluble in water | [InChIKey]
GBWAAJJGXQJTTA-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Fritillaria thunbergii. | [Uses]
Tubeimoside II (Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.
IC50 value:
Target:
The anti-inflammatory, anti-tumor, and anti-tumorigenic activities of tubeimoside II are stronger than those of tubeimoside I, and the acute toxicity of tubeimoside II is lower than that of tubeimoside I; the anti-inflammatory, anti-tumor, and anti-tumorigenic activities of tubeimoside III are stronger than those of tubeimoside II, and the acute toxicity of tubeimoside III is also stronger than that of tubeimoside II. | [target]
Immunology & Inflammation related | [References]
[1] Yu TX, et al. Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects. Acta Pharmacol Sin. 2001 May;22(5):463-8. PMID:11743898 |
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