| Identification | Back Directory | [Name]
2H-3,9a-Methano-1-benzoxepin-4,5,6,7,9,10-hexol,5a-[(acetyloxy)methyl]octahydro-2,2,9-trimethyl-, 4,6,7,10-tetraacetate5-benzoate, (3R,4R,5S,5aS,6R,7S,9S,9aS,10R)- | [CAS]
116159-73-0 | [Synonyms]
Celangulin
AngulatinJ
CelangulinQ: What is
Celangulin Q: What is the CAS Number of
Celangulin
2H-3,9a-Methano-1-benzoxepin-4,5,6,7,9,10-hexol,5a-[(acetyloxy)methyl]octahydro-2,2,9-trimethyl-, 4,6,7,10-tetraacetate5-benzoate, (3R,4R,5S,5aS,6R,7S,9S,9aS,10R)- | [Molecular Formula]
C32H40O14 | [MOL File]
116159-73-0.mol | [Molecular Weight]
648.65 |
| Hazard Information | Back Directory | [Chemical Properties]
Pure celangulin is a white, amorphous powder that is non-volatile and relatively stable to light and heat. It is readily soluble in organic solvents such as ethanol, acetone, ether, and chloroform. Celangulin is safe for higher animals. Oral administration of 6000 mg/kg of root bark powder to mice revealed no obvious symptoms of poisoning. It is non-irritating to the eyes and skin and is safe for birds, aquatic animals, bees, and major natural enemies of insect pests. It is highly effective against some Lepidoptera, Orthoptera, and Coleoptera pests. Its primary mode of action is stomach poisoning; it has no contact or fumigant effects. | [Uses]
Celangulin is an insecticidal component isolated from Celastrus angulatus. Celangulin activates the calcium channel on the plasma membrane with increasing the intracellular Ca2+ after influx from the external. Celangulin activates the calcium channel in the ER[1]. | [References]
[1] Li Y, et
al. Modulation of the Ca(2+)
signaling pathway by celangulin I in the central neurons of Spodoptera exigua.
Pestic Biochem Physiol. 2016 Feb;127:76-81. DOI:10.1016/j.pestbp.2015.09.010 |
|
|