| Identification | Back Directory | [Name]
aklaviketone | [CAS]
116235-59-7 | [Synonyms]
aklaviketone (1R,2R)-2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-1β-naphthacenecarboxylic acid methyl ester 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-, methyl ester, (1R,2R)- | [Molecular Formula]
C22H18O8 | [MOL File]
116235-59-7.mol | [Molecular Weight]
410.37 |
| Hazard Information | Back Directory | [Uses]
Aklaviketone is a bacterial metabolite found in strain S 383 of Streptomyces galilaeus. Aklaviketone can be used in the biosynthetic pathway of anthracycline antibiotics[1]. | [Definition]
ChEBI: A carboxylic ester that is the methyl ester of (1R,2R)-2-ethyl-2,5,7-trihydroxy-4,6,11-trioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylic acid. | [References]
[1] Eckardt K, et al. Biosynthesis of anthracyclinones: isolation of a new early cyclization product aklaviketone. J Antibiot (Tokyo). 1988 Jun;41(6):788-93. DOI:10.7164/antibiotics.41.788 |
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