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116235-59-7

116235-59-7 Structure

116235-59-7 Structure
IdentificationBack Directory
[Name]

aklaviketone
[CAS]

116235-59-7
[Synonyms]

aklaviketone
(1R,2R)-2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-1β-naphthacenecarboxylic acid methyl ester
1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-, methyl ester, (1R,2R)-
[Molecular Formula]

C22H18O8
[MOL File]

116235-59-7.mol
[Molecular Weight]

410.37
Hazard InformationBack Directory
[Uses]

Aklaviketone is a bacterial metabolite found in strain S 383 of Streptomyces galilaeus. Aklaviketone can be used in the biosynthetic pathway of anthracycline antibiotics[1].
[Definition]

ChEBI: A carboxylic ester that is the methyl ester of (1R,2R)-2-ethyl-2,5,7-trihydroxy-4,6,11-trioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylic acid.
[References]

[1] Eckardt K, et al. Biosynthesis of anthracyclinones: isolation of a new early cyclization product aklaviketone. J Antibiot (Tokyo). 1988 Jun;41(6):788-93. DOI:10.7164/antibiotics.41.788
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