| Identification | Back Directory | [Name]
ENTEROSTATIN (PIG, RAT) | [CAS]
117137-85-6 | [Synonyms]
V-P-D-P-R
Enterostatin(rat)
VAL-PRO-ASP-PRO-ARG
ENTEROSTATIN (PIG, RAT)
H-VAL-PRO-ASP-PRO-ARG-OH
ENTEROSTATIN, PORCINE, RAT
ENTEROSTATIN (PIG, RAT) USP/EP/BP
L-Arginine, L-valyl-L-prolyl-L-α-aspartyl-L-prolyl- | [Molecular Formula]
C25H42N8O8 | [MDL Number]
MFCD00133917 | [MOL File]
117137-85-6.mol | [Molecular Weight]
582.65 |
| Hazard Information | Back Directory | [Uses]
Enterostatin (rat), an orally active activation peptide of procolipase, selectively reduces fat intake. Enterostatin (rat) reduces serum cholesterol levels by way of a CCK1 receptor-dependent mechanism[1][2]. | [in vivo]
Enterostatin (rat) (50-100 mg/kg; p.o.) has a hypocholesterolemic effect mediated by CCK1 receptor in male ddY mice[1]. | Animal Model: | Male ddY mice[1] | | Dosage: | 50 and 100 mg/kg | | Administration: | Oral administration | | Result: | Reduced serum cholesterol levels after oral administration at a dose of 100 mg/kg. |
| [References]
[1] Takenaka Y, et, al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. DOI:10.1016/j.peptides.2008.08.021
[2] Erlanson-Albertsson C, et, al. Pancreatic procolipase propeptide, enterostatin, specifically inhibits fat intake. Physiol Behav. 1991 Jun;49(6):1191-4. DOI:10.1016/0031-9384(91)90350-w |
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