| Identification | Back Directory | [Name]
1,7-Dimethylxanthine-[13C4,15N3] (paraxanthine) | [CAS]
1173018-79-5 | [Synonyms]
1,7-Dimethylxanthine-2,4,5,6-13C?-1,3,9-1?N?
13C4,15N3]-1,7-Dimethylxanthine(paraxanthine)
1,7-Dimethylxanthine-2,4,5,6-13C4-1,3,9-15N3
1,7-Dimethylxanthine (paraxanthine, 2,4,5,6-13C4 1,3,9-15N3)
1,7-Dimethylxanthine-2,4,5,6-13C4-1,3,9-15N3 >=98 atom %, >=98% (CP)
N-(4-(2,4-difluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-2-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-5-yl)acetamide, potassium salt | [Molecular Formula]
C7H8N4O2 | [MDL Number]
MFCD11656179 | [MOL File]
1173018-79-5.mol | [Molecular Weight]
187.227 |
| Chemical Properties | Back Directory | [Melting point ]
294-296°C | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (slightly, Heated) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Paraxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74(4):980-9. DOI:10.1124/mol.108.048207 |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|