| Identification | Back Directory | [Name]
4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE | [CAS]
1173023-85-2 | [Synonyms]
GW 583340 DIHYDROCHLORIDE
4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE
N-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYL]-6-[2-[[[2-(METHYLSULFONYL)ETHYL]AMINO]METHYL]-4-THIAZOLYL]-4-QUINAZOLINAMINE DIHYDROCHLORIDE | [Molecular Formula]
C28H27Cl3FN5O3S2 | [MDL Number]
MFCD07370137 | [MOL File]
1173023-85-2.mol | [Molecular Weight]
671.03 |
| Hazard Information | Back Directory | [Uses]
GW 583340 dihydrochloride is a potent inhibitor of EGFR/ErbB2 reducing multi-drug resistance in cancer cells. Used in breast cancer treatment. | [Biological Activity]
Potent dual ErbB-2/EGFR tyrosine kinase inhibitor. IC50= 0.01 and 0.014 μM for EGFR and ErbB-2. Orally active. | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
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https://www.bocsci.com |
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R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
| Company Name: |
Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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SIGMA-RBI
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800 736 3690 (Orders) |
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www.sigma-aldrich.com |
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