| Identification | Back Directory | [Name]
BPV(BIPY) | [CAS]
1173697-60-3 | [Synonyms]
BPV(BIPY)
POTASSIUM BISPEROXO(BIPYRIDINE)OXOVANADATE (V) | [Molecular Formula]
C10H10KN2O6V | [MDL Number]
MFCD01862577 | [MOL File]
1173697-60-3.mol | [Molecular Weight]
344.24 |
| Hazard Information | Back Directory | [Uses]
bpV(bipy) hydrate is the inhibitor for phosphoinositide 3-phosphatase (PTEN) and protein tyrosine phosphatases (PTP-β and PTP-1B) with IC50s of 18, 60.3, and 164 nM, respectively[1]. | [Biological Activity]
Cell permeable: no''Primary Target
phosphotyrosine phosphatase''Product does not compete with ATP.''Reversible: no''Target IC50: 18 nM against PTEN''Target Ki: 100 nM for phosphotyrosine phosphatase | [References]
[1] Schmid AC, et al., Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004 May 21;566(1-3):35-8. DOI:10.1016/j.febslet.2004.03.102 |
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