| Identification | Back Directory | [Name]
hDHODH-IN-1 | [CAS]
1173715-42-8 | [Synonyms]
hDHODH-IN-1
2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy- | [Molecular Formula]
C17H14N2O2 | [MDL Number]
MFCD32671346 | [MOL File]
1173715-42-8.mol | [Molecular Weight]
278.31 |
| Chemical Properties | Back Directory | [Melting point ]
270-275 °C (decomp) | [Boiling point ]
514.6±50.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 250 mg/mL (898.28 mM) | [form ]
Solid | [pka]
5.20±0.50(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1]. | [storage]
Store at -20°C | [References]
[1] Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9(2):e87960. DOI:10.1371/journal.pone.0087960 |
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