| Identification | Back Directory | [Name]
1H-Pyrimido[5,4-b][1,4]benzothiazin-2(3H)-one, 3-β-D-ribofuranosyl- | [CAS]
1174063-74-1 | [Synonyms]
Tricyclic cytosine tC
1H-Pyrimido[5,4-b][1,4]benzothiazin-2(3H)-one, 3-β-D-ribofuranosyl- | [Molecular Formula]
C15H15N3O5S | [MOL File]
1174063-74-1.mol | [Molecular Weight]
349.36 |
| Hazard Information | Back Directory | [Uses]
Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm[1][2]. | [References]
[1] Sandin P, Lincoln P, Brown T, Wilhelmsson LM. Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe. Nat Protoc. 2007;2(3):615-23. DOI:10.1038/nprot.2007.80
[2] Manetto A, et al. tC, tCo and tCnitro: Tricyclic Cytosine Probes of DNA and RNA Structure. The Glen Report. 2010, 22(13). |
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