| Chemical Properties | Back Directory | [density ]
1.443±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
9.918±0.70(predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Dasatinib analog-1 (compound 5826) inhibits CYP3A4 viability with a Ki value of 5.4 μM. Dasatinib analog-1 blocks the formation of glutathione adducts[1]. | [References]
[1] Xiaohai Li, et al. Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways. Drug Metab Dispos. 2009, 37, 6. DOI:10.1124/dmd.108.025932 |
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