| Identification | Back Directory | [Name]
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Mesylate | [CAS]
1175536-50-1 | [Synonyms]
EP-F
Efinaconazole int2
Efinaconazole Impurity 44
Efinaconazole Related Impurity 7
Efinaconazole Related Impurity 7 Mesylate
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Mesylate
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol methanesulfonate
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol with methanesulfonate
1-[(2R,3R)-2-(2,4-difluorophenyl)-2,3-dihydroxybutyl]-1 H-[1,2,4]triazole methanesulfonate salt | [EINECS(EC#)]
815-196-0 | [Molecular Formula]
C13H15F2N3O4S | [MDL Number]
MFCD28964178 | [MOL File]
1175536-50-1.mol | [Molecular Weight]
347.338 |
| Chemical Properties | Back Directory | [Melting point ]
173.5-174.5℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Sparingly), Methanol (Slightly) | [form ]
Solid | [color ]
Off White to Pale Beige | [Stability:]
Hygroscopic |
| Questions And Answer | Back Directory | [Uses]
(2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is a useful synthetic intermediate in the synthesis of Efinaconazole; a topical antifungal for onychomycosis. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is also used as a reagent in the synthesis of Ravuconazole; an ergosterol biosynthesis inhibitor and antifungal. |
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