| Identification | Back Directory | [Name]
H-PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP-OH | [CAS]
117620-76-5 | [Synonyms]
tuna AI
PTHIKWGD
PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP
H-PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP-OH
L-Prolyl-L-threonyl-L-histidyl-L-isoleucyl-L-lysyl-L-tryptophylglycyl-L-aspartic acid | [Molecular Formula]
C44H64N12O12 | [MDL Number]
MFCD00153586 | [MOL File]
117620-76-5.mol | [Molecular Weight]
953.05 |
| Chemical Properties | Back Directory | [Boiling point ]
1460.5±65.0 °C(Predicted) | [density ]
1.351±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [pka]
2.88±0.10(Predicted) | [Sequence]
Pro-Thr-His-Ile-Lys-Trp-Gly-Asp |
| Hazard Information | Back Directory | [Uses]
Tuna AI, an angiotensin-converting enzyme (ACE) inhibitor, exhibits IC50 values of 1 μM and 2 μM for ACEs from bovine and rabbit lungs, respectively[1]. | [References]
[1] Y Kohama, et al. Isolation of angiotensin-converting enzyme inhibitor from tuna muscle. Biochem Biophys Res Commun. 1988 Aug 30;155(1):332-7. DOI:10.1016/s0006-291x(88)81089-1 |
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