| Identification | Back Directory | [Name]
Dehydrojuncusol | [CAS]
117824-04-1 | [Synonyms]
Dehydrojuncusol
2,7-Phenanthrenediol, 5-ethenyl-1,6-dimethyl- | [Molecular Formula]
C18H16O2 | [MDL Number]
MFCD34470949 | [MOL File]
117824-04-1.mol | [Molecular Weight]
264.32 |
| Hazard Information | Back Directory | [Uses]
Dehydrojuncusol, a potent HCV inhibitor, targets HCV NS5A and is able to inhibit RNA replication of replicons harboring resistance mutations to anti-NS5A direct-acting antivirals. Dehydrojuncusol significantly inhibits HCV infection when added after virus inoculation of HCV genotype 2a (EC50=1.35?μM)[1]. | [References]
[1] Sahuc ME, et al. Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication. J Virol. 2019;93(10):e02009-18. Published 2019 May 1. DOI:10.1128/JVI.02009-18 |
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