ChemicalBook--->CAS DataBase List--->117857-45-1

117857-45-1

117857-45-1 Structure

117857-45-1 Structure
IdentificationBack Directory
[Name]

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride
[CAS]

117857-45-1
[Synonyms]

R-72063
Loreclezole
LoreclezoleHCl
1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole
1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole
1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-
(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole hydrochloride
[Molecular Formula]

C10H6Cl3N3
[MDL Number]

MFCD00865331
[MOL File]

117857-45-1.mol
[Molecular Weight]

274.53
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,2-8°C
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Anti-epileptic.
[Definition]

ChEBI: 1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole is a dichlorobenzene.
[Biological Activity]

Subtype-selective GABA A receptor modulator. Acts as a positive allosteric modulator of β 2 or β 3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABA A receptor sensitization. Inhibits homomeric ρ 1 GABA C receptors.
Spectrum DetailBack Directory
[Spectrum Detail]

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride(117857-45-1)1HNMR
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