| Identification | Back Directory | [Name]
cyprodime | [CAS]
118111-54-9 | [Synonyms]
Cyprodime hydrochloride
17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one
Morphinan-6-one, 17-(cyclopropylmethyl)-4,14-dimethoxy-
17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride | [Molecular Formula]
C22H29NO3 | [MOL File]
118111-54-9.mol | [Molecular Weight]
355.47 |
| Chemical Properties | Back Directory | [Melting point ]
155-159 °C(Solv: methanol (67-56-1)) | [Boiling point ]
504.0±50.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at +4°C | [solubility ]
Soluble to 100 mM in DMSO and to 100 mM in ethanol | [form ]
Powder | [pka]
7.42±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Selective μ-opioid receptor antagonist. Reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. | [Biological Activity]
Selective μ -opioid receptor antagonist (K i values are 5.4, 244.6 and 2187 nM for μ -, δ - and κ -opioid receptors respectively). Reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. |
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