118290-27-0

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118290-27-0 Structure

Identification	Back Directory
[Name] AF-DX 384
[CAS] 118290-27-0
[Synonyms] AF-DX 384 AF-DX 384 methanesulfonate N-(2-(2-((DIPROPYLAMINO)METHYL)PIPERIDIN-1-YL)ETHYL)-6-OXO-5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPINE-11(6H)-CARBOXAMIDE N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxami N-[2-[2-[(DIPROPYLAMINO)METHYL]-1-PIPERIDINYL]ETHYL]-5,6-DIHYDRO-6-OXO-11H-PYRIDO[2,3-B][1,4]BENZODIAZEPINE-11-CARBOXAMIDE
[Molecular Formula] C27H38N6O2
[MDL Number] MFCD00884624
[MOL File] 118290-27-0.mol
[Molecular Weight] 478.63

Chemical Properties	Back Directory
[storage temp. ] Store at RT

Hazard Information	Back Directory
[Uses] AF-DX 384 is a potent mAChR M2/mAChR M4?selective antagonist.
[Definition] ChEBI: N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide is a benzodiazepine.
[Biological Activity] Potent M 2 /M 4 selective antagonist (pK i values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human M 2 , M 4 , M 1 , M 3 and M 5 receptors respectively).

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