| Identification | Back Directory | [Name]
Benzamide, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]- | [CAS]
1187188-59-5 | [Synonyms]
Crisaborole Impurity 11
Crisaborole Impurity 53
Benzamide, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
4-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzamide
4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide | [Molecular Formula]
C14H12BNO4 | [MOL File]
1187188-59-5.mol | [Molecular Weight]
269.06 |
| Chemical Properties | Back Directory | [Melting point ]
>188°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [color ]
Pale Red to Red | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C14H12BNO4/c16-14(17)9-1-3-11(4-2-9)20-12-5-6-13-10(7-12)8-19-15(13)18/h1-7,18H,8H2,(H2,16,17) | [InChIKey]
BNNSMPLZLMPJQX-UHFFFAOYSA-N | [SMILES]
C(N)(=O)C1=CC=C(OC2=CC=C3B(O)OCC3=C2)C=C1 |
| Hazard Information | Back Directory | [Uses]
4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide is used in the preparation of substituted benzoxaborole and related boron-containing small molecules as anti-inflammatory agents. | [General Description]
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide, also known as Crisaborole Impurity 11, is an impurity of Crisaborole. Crisaborole topical is used to treat mild to moderate atopic dermatitis (eczema). |
|
| Company Name: |
TOSUN PHARM
|
| Tel: |
020-61855200 13326451905 |
| Website: |
www.toref.cn/ |
|