118719-16-7

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118719-16-7 Structure

Identification	Back Directory
[Name] N'-[(1E)-(5-bromo-2-hydroxyphenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide
[CAS] 118719-16-7
[Synonyms] dCeMM1 N'-(5-bromo-2-hydroxybenzylidene)-4-methylbenzenesulfonohydrazide N'-[(1E)-(5-bromo-2-hydroxyphenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide
[EINECS(EC#)] 657-003-0
[Molecular Formula] C14H13BrN2O3S
[MDL Number] MFCD00415337
[MOL File] 118719-16-7.mol
[Molecular Weight] 369.234

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H315-H335-H319
[Precautionary statements ] P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Hazard Information	Back Directory
[Uses] dCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells[1].
[References] [1] Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207.

Spectrum Detail	Back Directory
[Spectrum Detail] N'-[(1E)-(5-bromo-2-hydroxyphenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide(118719-16-7)¹HNMR

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