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1193111-65-7

1193111-65-7 Structure

1193111-65-7 Structure
IdentificationBack Directory
[Name]

N-[4-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxobutyl]glycylglycylglycyl-β-alanine 2,5-dioxo-1-pyrrolidinyl ester
[CAS]

1193111-65-7
[Synonyms]

[Molecular Formula]

C21H26N6O10
[MOL File]

1193111-65-7.mol
[Molecular Weight]

522.47
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[form ]

Solid
[pka]

14.01±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[References]

[1] Beck A, et, al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
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