| Identification | Back Directory | [Name]
1H-Pyrrole-2-carboxamide, 4-acetyl-N-[[4-[(aminosulfonyl)methyl]phenyl]methyl]- | [CAS]
1197904-57-6 | [Synonyms]
S07-2001
1H-Pyrrole-2-carboxamide, 4-acetyl-N-[[4-[(aminosulfonyl)methyl]phenyl]methyl]- | [Molecular Formula]
C15H17N3O4S | [MOL File]
1197904-57-6.mol | [Molecular Weight]
335.38 |
| Hazard Information | Back Directory | [Uses]
S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer agent resistance[1]. | [References]
[1] Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022. |
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