ChemicalBook--->CAS DataBase List--->1198621-84-9

1198621-84-9

1198621-84-9 Structure

1198621-84-9 Structure
IdentificationBack Directory
[Name]

ODN D-SL01
[CAS]

1198621-84-9
[Synonyms]

ODN D-SL01
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
[Sequence]

DNA, d(P-thio)(T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A)
Hazard InformationBack Directory
[Uses]

ODN D-SL01, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. ODN D-SL01 has strong immunostimulatory activity in a variety of vertebrate species and has anticancer activity. ODN D-SL01 sequence: 5'- T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A-3'[1].
[References]

[1] Liang Yang, et al. CpG oligodeoxynucleotides with double stem-loops show strong immunostimulatory activity. Int Immunopharmacol. 2013 Jan;15(1):89-96 DOI:10.1016/j.intimp.2012.10.020
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