| Identification | Back Directory | [Name]
Mycophenolic acid-13C17 | [CAS]
1202866-92-9 | [Synonyms]
13C17-Mycophenolic Acid
Mycophenolic acid-13C17 solution
13C17]-Mycophenolic acid-100μg/mL in ACN
Mycophenolic acid-13C17 | [EINECS(EC#)]
200-835-2 | [Molecular Formula]
C17H20O6 | [MDL Number]
MFCD16652528 | [MOL File]
1202866-92-9.mol | [Molecular Weight]
337.49 |
| Hazard Information | Back Directory | [Uses]
Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. DOI:10.1177/1071100718790255
[2] Sophie Domhan, et al. Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid. Mol Cancer Ther.?2008 Jun;7(6):1656-68. DOI:10.1158/1535-7163.MCT-08-0193
[3] Stephen R Welch, et al. Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform. Viruses.?2021 Jun 28;13(7):1255. DOI:10.3390/v13071255 |
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 13060007561 |
| Website: |
www.sigmaaldrich.com |
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