| Identification | Back Directory | [Name]
PNU-159682 carboxylic acid | [CAS]
1204819-92-0 | [Synonyms]
PNU-159682 carboxylic acid
2-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-4-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-6,11-dioxo-, (2S,4S)- | [Molecular Formula]
C31H33NO13 | [MDL Number]
MFCD32263383 | [MOL File]
1204819-92-0.mol | [Molecular Weight]
627.59 |
| Chemical Properties | Back Directory | [Boiling point ]
840.8±65.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.24±0.40(Predicted) | [color ]
Brown to red |
| Hazard Information | Back Directory | [Uses]
PNU-159682 carboxylic acid (compound 53) is a potent ADCs cytotoxin and encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid has protein fold and diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response[1]. | [IC 50]
Daunorubicins/Doxorubicins | [References]
[1] John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1. |
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YJ Pharma
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13962794339 13962794339 |
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