| Identification | Back Directory | [Name]
2-chloro-4,6-di(biphenyl-3-yl)-1,3,5-triazine | [CAS]
1205748-61-3 | [Synonyms]
2-Chloro-4,6-bis(3-biphenyl)1,3,5-triazine
2-chloro-4,6-di(biphenyl-3-yl)-1,3,5-triazine
2,4-di(biphenyl-3-yl)-6-chloro-1,3,5-triazine
2,4-bis([1,1-biphenyl]-3-yl)-6-chloro-1,3,5-Triazine
2,4-Di([1,1'-biphenyl]-3-yl)-6-chloro-1,3,5-triazine
1,3,5-triazine, 2,4-bis([1,1'-biphenyl]-3-yl)-6-chloro- | [Molecular Formula]
C27H18ClN3 | [MOL File]
1205748-61-3.mol | [Molecular Weight]
419.9 |
| Chemical Properties | Back Directory | [Boiling point ]
685.5±58.0 °C(Predicted) | [density ]
1.227±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [pka]
-0.17±0.10(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
1. 5.2 g of magnesium (0.215 mol) was added to a 500 mL four-necked flask and 50 g of 3-bromobiphenyl (214 mmol) dissolved in 200 mL of THF was added slowly and dropwise.
2. The reaction mixture was heated to reflux for 1.5 hours and subsequently cooled to room temperature.
3. in another flask, 17.2 g of cyanuric chloride (93 mmol) was dissolved in 150 mL of THF and the solution was cooled to 0°C.
4. The Grignard reagent prepared in step 1 was slowly added to the cooled cyanuric chloride solution and the reaction mixture was stirred for 12 hours at room temperature.
5. Upon completion of the reaction, 150 mL of HCl (1 M) was added to the mixture for acidification, and the aqueous phase was extracted with dichloromethane three times (50 mL each time).
6. The organic phases were combined, washed with deionized water, dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure to remove the solvent.
7. The crude product was recrystallized from ethanol to give 32.8 g (78 mmol) of pure product in 84% yield. | [References]
[1] Patent: KR2016/28524, 2016, A. Location in patent: Paragraph 0221-0223
[2] Patent: JP2016/6039, 2016, A. Location in patent: Paragraph 0109; 0110 |
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