| Identification | Back Directory | [Name]
oxetan-3-yl-acetic acid ethyl ester | [CAS]
1207175-04-9 | [Synonyms]
ethyl 2-(oxetan-3-yl)acetate
3-Oxetaneacetic acid, ethyl ester
oxetan-3-yl-acetic acid ethyl ester | [Molecular Formula]
C7H12O3 | [MDL Number]
MFCD14586417 | [MOL File]
1207175-04-9.mol | [Molecular Weight]
144.17 |
| Hazard Information | Back Directory | [Uses]
With the structure oxetane, oxetan-3-yl-acetic acid ethyl ester can be used as drug intermediate. In medicinal chemistry, oxetanes have received enormous interest as replacement groups for gem-dimethyl and carbonyl groups with improved physicochemical properties. The small, polar nature of the heterocycle has led to its incorporation as a pendant motif to improve druglike properties.[1] | [References]
[1] Oxetanes: Recent Advances in Synthesis, Reactivity, and Medicinal Chemistry. Rev. 2016, 116, 19, 12150–12233. DOI:10.1021/acs.chemrev.6b00274
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