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1210828-09-3

1210828-09-3 Structure

1210828-09-3 Structure
IdentificationBack Directory
[Name]

5-[2-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]ethyl]-5-azaspiro[2.4]heptan-7-ol
[CAS]

1210828-09-3
[Synonyms]

[Molecular Formula]

C27H28FN3O4
[MOL File]

1210828-09-3.mol
[Molecular Weight]

477.53
Chemical PropertiesBack Directory
[Boiling point ]

683.7±55.0 °C(Predicted)
[density ]

1.40±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

14.78±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Veonetinib (example 3) is a potent inhibitor of tyrosine kinase, with the IC50 of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively[1].
[References]

[1] Advenchen Laboratories, LLC. Kinase inhibitors for the treatment of disease associated with angiogenesis. World Intellectual Property Organization, WO2010021918 A1 2010-02-25
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