| Identification | Back Directory | [Name]
tert-butyl 5-(5(ethoxymethoxy)benzofural-2-yl)-6-nitropyridin-2-yl(methyl)ccarbamate | [CAS]
1211333-20-8 | [Synonyms]
tert-butyl 5-(5(ethoxymethoxy)benzofural-2-yl)-6-nitropyridin-2-yl(methyl)ccarbamate | [Molecular Formula]
C22H25N3O7 | [MOL File]
1211333-20-8.mol | [Molecular Weight]
443.45 |
| Chemical Properties | Back Directory | [Boiling point ]
593.4±50.0 °C(Predicted) | [density ]
1.275±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
-2.37±0.10(Predicted) | [color ]
Light green to yellow green |
| Hazard Information | Back Directory | [Uses]
AZD4694 Precursor (AZ13040214) is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1]. | [Biological Activity]
[18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1].
18F-AZD4694 is an amyloid-β imaging ligand with high affinity for amyloid-β plaques. 18F-AZD4694 is a high affinity (Kd= 2.3 nM) radioligand for imaging amyloid-β plaques that displays lower white matter binding compared to other fluorinated amyloid-PET tracers, enabling easier visual reads[1]. | [References]
[1]. Therriault J, et al. Determining Amyloid-β Positivity Using 18F-AZD4694 PET Imaging. J Nucl Med. 2021;62(2):247-252. |
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