| Identification | Back Directory | [Name]
(S)-(+)-DIMETHINDENE MALEATE | [CAS]
121367-05-3 | [Synonyms]
Zinc01481789
(S)-(+)-Dimethindene
(S)-(+)-DIMETHINDENE MALEATE
N,N-DIMETHYL-3-[(1S)-1-(2-PYRIDINYL)ETHYL]-1H-INDENE-2-ETHANAMINE MALEATE | [Molecular Formula]
C20H24N2 | [MDL Number]
MFCD03701358 | [MOL File]
121367-05-3.mol | [Molecular Weight]
292.42 |
| Hazard Information | Back Directory | [Uses]
(S)-(+)-Dimethindene Maleate is a subtype-selective mAChR M2 antagonist and histamine H1 receptor antagonist. | [Definition]
ChEBI: N,N-dimethyl-2-[3-[(1S)-1-(2-pyridinyl)ethyl]-1H-inden-2-yl]ethanamine is an indene. | [Biological Activity]
Enantiomer that is a subtype-selective M 2 muscarinic receptor antagonist (pK i values are 7.08, 7.78, 6.70 and 7.00 for M 1 , M 2 , M 3 and M 4 receptors respectively). Also H 1 histamine receptor antagonist (pK i = 7.48). |
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