| Identification | Back Directory | [Name]
AN-3485 | [CAS]
1213827-99-6 | [Synonyms]
AN-3485
[3-chloro-4-[(1-hydroxy-3H-2,1-benzoxaborol-6-yl)oxy]phenyl]methanamine
6-[4-(Aminomethyl)-2-chlorophenoxy]-2,1-benzoxaborol-1(3H)-ol hydrochloride | [Molecular Formula]
C14H13BClNO3 | [MDL Number]
MFCD25977112 | [MOL File]
1213827-99-6.mol | [Molecular Weight]
289.52 |
| Chemical Properties | Back Directory | [Boiling point ]
424.2±55.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
7.00±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. | [IC 50]
TLR2; TLR3; TLR4; TLR5 | [References]
[1] Dong C, et al. Inhibition of Toll-like receptor-mediated inflammation in vitro and in vivo by a novelbenzoxaborole. J Pharmacol Exp Ther. 2013 Feb;344(2):436-46. DOI:10.1124/jpet.112.200030 |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
MedChemExpress
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021-58955995 |
| Website: |
www.medchemexpress.com |
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