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121524-18-3

121524-18-3 Structure

121524-18-3 Structure
IdentificationBack Directory
[Name]

FK 453
[CAS]

121524-18-3
[Synonyms]

FK 453
2-Propen-1-one,1-[(2R)-2-(2-hydroxyethyl)-1-piperidinyl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3yl)-,(2E)-
[Molecular Formula]

C23H25N3O2
[MDL Number]

MFCD00880201
[MOL File]

121524-18-3.mol
[Molecular Weight]

375.46
Chemical PropertiesBack Directory
[density ]

1.21±0.1 g/cm3(Predicted)
[pka]

15.15±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

FK 453 (compound 1d) is a potent and selective adenosine A1 receptor antagonist with an IC50 value of 17.2 nM[1].
[References]

[1] Atsushi Akahane, et al. Discovery of FK453, a novel non-xanthine adenosine A1 receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 1996, 16, 7.
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