| Identification | Back Directory | [Name]
Medetomidine-13C,d3 Hydrochloride | [CAS]
1216630-06-6 | [Synonyms]
Medetomidine-13C,d3 Hydrochloride
[13C,2H3]-Medetomidine Hydrochloride
4-[1-(2,3-DiMethylphenyl)ethyl-13C,d3]-1H-iMidazole
5-[2,2,2-trideuterio-1-(2,3-dimethylphenyl)(2^{13}C)ethyl]-1~{H}-imidazole | [Molecular Formula]
C13H16ClN2 | [MOL File]
1216630-06-6.mol | [Molecular Weight]
235.733 |
| Chemical Properties | Back Directory | [Melting point ]
162-164°C | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
Methanol (Slightly) | [form ]
Solid | [color ]
White to Pale Yellow |
| Safety Data | Back Directory | [WGK Germany ]
WGK 2 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1 |
| Hazard Information | Back Directory | [Description]
Medetomidine-13C-d3 is intended for use as an internal standard for the quantification of medetomidine by GC- or LC-MS. Medetomidine is an imidazole compound that selectively binds to α2-adrenergic receptors (α2-ARs) over α1-ARs (Kis = 1.08 and 1,800 nM, respectively). | [Chemical Properties]
White Solid | [Uses]
Labelled α2-adrenergic agonist. Sedative; analgesic. | [in vivo]
Medetomidine (200 μg/kg, p.o. or i.m.) hydrochloride induces a sedation in cats[5].
Medetomidine (20 μg/kg, i.v.) hydrochloride shows sedative and analgesic effects in dogs[6].
Medetomidine (0.05-0.3 mg/kg, s.c.) hydrochloride protects against Diazinon-induced toxicosis in mice[7].
| [References]
[1] O. VAINIO T. V V. Reversal of medetomidine sedation by atipamezole in dogs[J]. Journal of veterinary pharmacology and therapeutics, 1990, 13 1: 15-22. DOI: 10.1111/j.1365-2885.1990.tb00742.x |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|