| Identification | Back Directory | [Name]
3, 3'-Diiodo-L-thyronine-(phenoxy-13C6) (T2) | [CAS]
1217459-13-6 | [Synonyms]
T2-13C6
13C6]-3,3'-Diiodothyronine
13C6]-L-3,3′-Diiodothyronine (T2)
L-3,3'-Diiodothyronine-[13C6] (T2)
3,3'-Diiodothyronine-[13C6] (Solution)
3, 3'-Diiodo-L-thyronine-(phenoxy-13C6) (T2)
l-3,3'-Diiodothyronine (t2) (phenoxy-13c6, 99%)
L-3,3'-Diiodothyronine-[13C6] (T2) (CertiMass solution)
3, 3′-Diiodo-L-thyronine-(phenoxy-13C?) (T2) hydrochloride
L-3,3'-DIIODOTHYRONINE (T2) (PHENOXY-13C6, 99%) CHEMICAL PURITY 97%
3, 3'-Diiodo-L-thyronine-(phenoxy-13C6) (T2) 99 atom % 13C, 97% (CP)
L-3,3'-DIIODOTHYRONINE (T2) (PHENOXY-13C6, 99%) 100 UG/ML IN 0.1N AMMONIA IN METHANOL | [Molecular Formula]
C15H13I2NO4 | [MDL Number]
MFCD15144879 | [MOL File]
1217459-13-6.mol | [Molecular Weight]
531.131 |
| Hazard Information | Back Directory | [Uses]
3,3'-Diiodo-L-thyronine-13C6 is the 13C labeled 3,3'-Diiodo-L-thyronine[1]. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[2][3]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3'-diiodo-L-thyronine (3,3'-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88. DOI:10.3389/fendo.2019.00088
[3] Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb99(1):89-94. DOI:10.1016/0303-7207(94)90150-3
[4] Chen X, et al. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun32(6):e4185. DOI:10.1002/bmc.4185 |
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