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1217667-10-1

1217667-10-1 Structure

1217667-10-1 Structure
IdentificationBack Directory
[Name]

Ropivacaine-d7 Hydrochloride
[CAS]

1217667-10-1
[Synonyms]

[2H7]-Ropivacaine HCl
Ropivacaine-d7 Hydrochloride
(–)-Ropivacaine-d7 hydrochloride
(2S)-N-(2,6-dimethylphenyl)-1-(1,1,2,2,3,3,3-heptadeuteriopropyl)piperidine-2-carboxamide:hydrochloride
[Molecular Formula]

C17H27ClN2O
[MOL File]

1217667-10-1.mol
[Molecular Weight]

310.87
Chemical PropertiesBack Directory
[Melting point ]

>245°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Sparingly), Water (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Water Solubility ]

Water: soluble
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]


GHS05
[Signal word ]

Danger
[Hazard statements ]

H318
[Precautionary statements ]

P280-P305+P351+P338-P310
Hazard InformationBack Directory
[Description]

(–)-Ropivacaine-d7 is intended for use as an internal standard for the quantification of (–)-ropivacaine by GC- or LC-MS. (–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
[Chemical Properties]

White Solid
[Uses]

Labelled Ropivacaine (R675000). Anesthetic (local).
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