Identification | Back Directory | [Name]
Ropivacaine-d7 Hydrochloride | [CAS]
1217667-10-1 | [Synonyms]
[2H7]-Ropivacaine HCl Ropivacaine-d7 Hydrochloride (–)-Ropivacaine-d7 hydrochloride (2S)-N-(2,6-dimethylphenyl)-1-(1,1,2,2,3,3,3-heptadeuteriopropyl)piperidine-2-carboxamide:hydrochloride | [Molecular Formula]
C17H27ClN2O | [MOL File]
1217667-10-1.mol | [Molecular Weight]
310.87 |
Chemical Properties | Back Directory | [Melting point ]
>245°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Sparingly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
Water: soluble | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Description]
(–)-Ropivacaine-d7 is intended for use as an internal standard for the quantification of (–)-ropivacaine by GC- or LC-MS. (–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth. | [Chemical Properties]
White Solid | [Uses]
Labelled Ropivacaine (R675000). Anesthetic (local). |
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
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