| Identification | Back Directory | [Name]
cis-3-Aminocyclobutanol h... | [CAS]
1219019-22-3 | [Synonyms]
CIS-3-AMINOCYCLOBUTANOL HCL
cis-3-Aminocyclobutanol h...
cis-3-AMinocyclobutanol hydrochloride
cis-3-Aminocyclobutan-1-ol hydrochloride
3-aminocyclobutan-1-ol hydrochloride, cis
(1S,3S)-3-aminocyclobutanol hydrochloride
Cyclobutanol, 3-aMino-, hydrochloride, cis-
(1s,3s)-3-aMinocyclobutan-1-ol hydrochloride
cis-3-Aminocyclobutanol hydrochloride - A0711
Cyclobutanol, 3-amino-, hydrochloride (1:1),cis- | [Molecular Formula]
C4H10ClNO | [MDL Number]
MFCD17214231 | [MOL File]
1219019-22-3.mol | [Molecular Weight]
123.581 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
powder | [color ]
White | [InChI]
InChI=1/C4H9NO.ClH/c5-3-1-4(6)2-3;/h3-4,6H,1-2,5H2;1H/t3-,4+; | [InChIKey]
XUMSHCRPQCZRGX-HKTIBRIUNA-N | [SMILES]
N[C@@H]1C[C@H](O)C1.Cl |&1:1,3,r| |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of cis-3-aminocyclobutanol hydrochloride from tert-butyl (cis-3-hydroxycyclobutyl)carbamate: tert-butyl (1S,3S)-3-hydroxycyclobutylcarbamate (see Preparation 4A; 187 mg, 1 mmol, 1.0 equiv.) was dissolved in 4N HCl/MeOH solution (15 mL), and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated to afford (1S,3S)-3-aminocyclobutanol hydrochloride (120 mg, 0.98 mmol, 98% yield).ESI-MS (M+1): 88 (calculated value C4H9NO: 87). | [References]
[1] Patent: WO2011/143366, 2011, A1. Location in patent: Page/Page column 144 |
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